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本文报告了5例淋巴组织疾病的免疫组化特征。例1为结节病,上皮样结节间淋巴细胞呈现全T(+)T_H(+);例2,5为B细胞来源的淋巴瘤,瘤细胞示全T(-),T_H(-)和T_S(-);另2例是T细胞淋巴瘤,其中例3瘤细胞示全T(+),T_H(-)和T_S(+),而例4瘤细胞为全T(+),T_H(+)和T_S(-)。作者认为仅根据形态学常难以区分淋巴瘤各个亚型以及未分化癌,单克隆抗体用于鉴别诊断是必要的。
This article reports the immunohistochemical features of five lymphoid disorders. Example 1 is sarcoidosis, epithelial-like nodular lymphocytes showed full T (+) T_H (+); cases 2 and 5 for B cell-derived lymphoma, tumor cells showed T (-), T_H And T_S (-). The other two cases were T-cell lymphoma. The tumor cells in Example 3 showed all T (+), T_H (-) and T_S (+), (+) And T_S (-). According to the authors, it is often difficult to distinguish between each subtypes of lymphoma and undifferentiated carcinoma based on morphology alone. Monoclonal antibodies are necessary for differential diagnosis.