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目的探讨老年高血压合并高脂血症并发缺血性心脏病的高危因素。方法选取2009年2月～2011年2月入住某院的老年高血压患者96例,其中并发高脂血症的54例患者为观察组,未并发高脂血症的的42例患者对照组。观察患者年龄、家族史、吸烟史、饮食控制情况、糖尿病史、高血压病史时间、甘油三酯水平、总胆固醇水平、血尿酸水平、血清超敏c反应蛋白水平、心电图、冠状动脉造影等。结果观察组患者缺血性心脏病发生率明显高于对照组(χ2=4.22,P﹤0.05);多因素Logistic回归分析发现老年高血压合并高脂血症患者并发缺血性心脏病的危险性与年龄、吸烟、高甘油三酯血症、高胆固醇血症、高水平超敏c反应蛋白、高尿酸血症有关。结论年龄、吸烟、高甘油三酯血症、高胆固醇血症、高水平超敏c反应蛋白、高尿酸血症是老年高血压合并高脂血症患者并发缺血性心脏病的高危因素。
Objective To investigate the risk factors of elderly hypertensive patients with hyperlipidemia complicated by ischemic heart disease. Methods 96 elderly hypertensive patients admitted to a hospital from February 2009 to February 2011 were selected. Among them, 54 patients with hyperlipidemia were observed in the observation group and 42 patients without hyperlipidemia. The patient’s age, family history, smoking history, diet control, history of diabetes, history of hypertension, triglyceride level, total cholesterol level, serum uric acid level, serum high-sensitivity c-reactive protein level, electrocardiogram and coronary angiography were observed. Results The incidence of ischemic heart disease in the observation group was significantly higher than that in the control group (χ2 = 4.22, P <0.05). Multivariate Logistic regression analysis found that the risk of ischemic heart disease in elderly patients with hypertension and hyperlipidemia And age, smoking, hypertriglyceridemia, hypercholesterolemia, high levels of hypersensitivity c-reactive protein, hyperuricemia related. Conclusions Age, smoking, hypertriglyceridemia, hypercholesterolemia, high level of CRP and hyperuricemia are the risk factors of ischemic heart disease in elderly patients with hypertension and hyperlipidemia.