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目的:评价腹腔注射复方苦参注射液联合顺铂治疗恶性腹腔积液的疗效。方法:将90例恶性腹腔积液患者随机分为2组,每组各45例。两组均行腹腔穿刺置管闭式引流术,并于腹腔内注入顺铂。试验组同时加复方苦参注射液腹腔内注入。比较两组疗效、生活质量改善和不良反应。结果:试验组总有效率及治疗前后生活质量改善率均高于对照组(P<0.01),不良反应发生率低于对照组(P<0.05)。结论:复方苦参注射液联合顺铂腹腔内注射治疗恶性腹腔积液比单用顺铂疗效更佳,提高患者生活质量效果更显著,不良反应轻微。
Objective: To evaluate the efficacy of intraperitoneal injection of Compound Kushen Injection and Cisplatin in the treatment of malignant ascites. Methods: Ninety patients with malignant ascites were randomly divided into two groups, 45 cases in each group. Both groups underwent peritoneal catheterization of closed drainage and intraperitoneal injection of cisplatin. The experimental group also added compound Kushen injection intraperitoneal injection. The curative effect, quality of life improvement and adverse reactions were compared between the two groups. Results: The total effective rate of the experimental group and the quality of life before and after treatment were higher than the control group (P <0.01), the incidence of adverse reactions was lower than the control group (P <0.05). Conclusion: Compound Kushen injection combined with cisplatin intraperitoneal injection of malignant ascites than cisplatin better curative effect to improve the quality of life of patients with more significant adverse reactions minor.