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本文报告我科1974～1982年住院猩红热378例,与青霉素问世前本病患者比较,有临床症状轻、皮疹多不典型、中毒性心肌炎和中毒性关节炎较多见、绝大多数为普通型,中毒型少见,脓毒型未见,病死率极低,变态反应性并发症(风湿热、肾小球性肾炎)极少见。诊断时要特别注意与中毒性休克综合征,金葡菌性猩红热、川崎病鉴别。有10％的致病菌对青霉素耐药,而对红霉素除个别株外皆敏感,故红霉素可作为治疗猩红热的首选药。
This article reports 378 cases of scarlet fever hospitalized in our hospital from 1974 to 1982. Compared with the patients with penicillin before the advent of the clinical symptoms of mild rash and atypical poisoning myocarditis and toxic arthritis are more common, the vast majority of ordinary type , Poisoning rare, no sepsis, very low case fatality, allergic complications (rheumatic fever, glomerulonephritis) are rare. Special attention to diagnosis and toxic shock syndrome, Staphylococcus aureus scarlet fever, Kawasaki disease identification. 10% of the pathogenic bacteria resistant to penicillin, and erythromycin in addition to individual strains are sensitive, so erythromycin can be used as the treatment of scarlet fever of choice.