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1979年在东非证实有抗氯喹株恶性疟存在。因此,推荐法西达(乙胺嘧啶25mg和周效磺胺500mg)作为该地区常规的疟疾预防性服药。本文描述了一个对法西达和氯喹都有抗性的病例。该病例为一个25岁的英国教师,从1982年2月20日在坦桑尼亚住了30周。入境前和居住期间每周服1片法西达。9月13日开始发热,血检证明为恶性疟。6天内服用氯喹2.2g(基质,下同)但10天后,血检仍有重度原虫血症,再服氯喹1.65g和3片法西达,略有好转。10月4日返回英国即入院检查,
In 1979, it was confirmed that there was anti-chloroquine-resistant falciparum malaria in East Africa. Therefore, fastidiac (pyrimethamine 25 mg and pTSX 500 mg) is recommended as a routine malaria prophylaxis in the region. This article describes a case of resistance to both faceidone and chloroquine. The case was a 25-year-old British teacher who lived in Tanzania for 30 weeks from February 20, 1982. Take 1 Faxidar weekly before and during your stay. September 13 fever, blood tests proved to be falciparum malaria. 6 days of taking chloroquine 2.2g (matrix, the same below) but after 10 days, blood still have severe parasitemia, and then served chloroquine 1.65g and 3 tablets of fesidacy, a slight improvement. October 4 returned to the United Kingdom that is admitted to hospital,