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目的:探讨胎传梅毒的诊断、防治要点。方法:回顾性分析63例胎传梅毒患儿的临床特点。结果:胎传梅毒患儿临床表现各异,确诊要靠辅助检查;部分患儿父母感染梅毒后未及时行正规治疗又隐瞒病史,导致诊断困难;未见对青霉素耐药的病例。结论:对有多器官功能损害而不能以现有疾病解释的患儿,应及时做梅毒螺旋体血凝试验和四肢长骨X线照片等检查。青霉素仍然是治疗梅毒的敏感的一线药物。
Objective: To investigate the diagnosis, prevention and treatment of fetal syphilis. Methods: Retrospective analysis of 63 cases of syphilis in children with clinical features. Results: The clinical manifestations of children with syphilis were different, the diagnosis depends on the auxiliary examination; some children infected with syphilis did not promptly after the regular treatment and concealed the history, leading to difficult diagnosis; no case of penicillin resistance. Conclusion: Children with multi-organ dysfunction that can not be explained by existing diseases should be promptly tested for Treponema pallidum hemagglutination test and long bones x-ray. Penicillin is still a sensitive first-line drug for treating syphilis.