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目的：探讨氟代他汀联合贝那普利治疗早期糖尿病肾病联合贝那普利治疗早期糖尿病肾病的临床疗效。方法将我院早期糖尿病患者随机分为治疗组（40例）与对照组（40例），治疗组使用氟代他汀联合贝那普利予常规胰岛素控制血糖及其他对症治疗，对照组予胰岛素降糖治疗及其他对症治疗，治疗半年后观察患者尿白蛋白排泄率、血肌酐、肾小球滤过率、血清总胆固醇含量，对观察指标进行统计对比。结果治疗组与对照组的治疗效果有统计学差异，治疗组肾功能改善情况明显高于对照组，血清总胆固醇含量低于对照组。结论氟代他汀联合贝那普利治疗早期糖尿病肾病能够改善肾功能，且无明显不良反应。“,”Objective: To investigate fluorinated statin combined with benazepril treatment of early diabetic nephropathy clinical efficacy combined with benazepril treatment of early diabetic nephropathy. Methods: Hospital early diabetic patients were randomly divided into treatment group (40 cases) and control group (40 cases), the treatment group using fluorinated statin combined with benazepril to regular insulin to control blood sugar and other symptomatic treatment and control group to insulin antidiabetic treatment and other symptomatic treatment, six months after treatment was observed in patients with urinary albumin excretion rate, serum creatinine, glomerular filtration rate, serum total cholesterol levels, statistical comparison of the observed indicators. Results: The effect of the treatment group and the control group were significantly different in the treatment group was significantly higher improvement in renal function, serum total cholesterol levels than the control group. Conclusion: fluorinated statin combined with benazepril treatment of early diabetic nephropathy can improve renal function, and no significant adverse reactions.