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对6例慢性肾功能衰竭患者采用治疗前的低蛋白饮食(LPD)后及LPD合并肾灵(LPD+EAA+KA)后自身对照的研究。结果显示:LDP+EAA+KA治疗后,Scr下降(P<0.01),Ccr提高(P<0.05),血BUN未有变化,血浆总必需氨基酸与总非必需氨基酸比率、支链氨基酸浓度均升高,且机体由负氮转为正氮平衡(P<0.005);蛋白质合成与分解率明显提高(P<0.001)。整个实验过程中,血浆钙、磷、总蛋白与白蛋白无明显变化。
Six patients with chronic renal failure after treatment with low protein diet (LPD) and LPD with Shen Ling (LPD + EAA + KA) self-control study. The results showed that Scr decreased (P <0.01), Ccr increased (P <0.05), blood BUN had no change after LDP + EAA + KA treatment, plasma total essential amino acid and total nonessential amino acid ratio, (P <0.005). The rate of protein synthesis and decomposition increased significantly (P <0.001). Throughout the experiment, plasma calcium, phosphorus, total protein and albumin no significant changes.