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为探讨阻塞性黄疸患者免疫功能的变化,采用红细胞C3b受体花环率、红细胞免疫复合物花环率、肿瘤红细胞花环率及CD+3、CD+4、CD+8细胞作为观测指标,测定了35例阻塞性黄疸患者免疫功能,并与30例正常人比较。结果显示:疾病组患者术前红细胞及T淋巴细胞免疫功能低于正常人(P<0.001),术后5天变化不大,术后14天较术前1天明显增高(P<0.05),但尚未恢复正常。提示解除胆道梗阻及切除肿瘤有助于阻塞性黄疸患者免疫功能的恢复。
In order to investigate the changes of immune function in patients with obstructive jaundice, the immunological function of 35 patients with obstructive jaundice was determined using the rosette of C3b receptor, the rosette of erythrocyte immune complex, the percentage of erythrocyte rosette, CD + 3, CD + 4 and CD + 8 cells Function, and compared with 30 normal subjects. The results showed that the preoperative immune function of erythrocytes and T lymphocytes in patients with disease group was lower than that in normal people (P <0.001), but the change was not obvious on the 5th day after operation and was significantly increased on the 14th day after operation compared with the first day before operation (P <0 .05), but not yet returned to normal. Tip to relieve biliary obstruction and removal of the tumor contribute to the recovery of immune function in patients with obstructive jaundice.