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易蒙停是用于控制急性非特异性和慢性腹泻的一种乙酰胺衍生物,为肠壁阿片受体的激动剂,可阻止乙酰胆碱和前列腺素的释放,从而抑制肠蠕动,延长内容物的滞留时间。易蒙停可增强肛门括约肌的张力,因此可抑制大便失禁和便急。 氟哌酸是目前临床上常用于治疗腹泻的药物之一。它通过抑制敏感菌群而减少细菌毒素对肠道的刺激作用而止泻。 易蒙停于70年代初开始应用于临床,国外报告疗效显著,国内尚较少系统性研究报告。本试验以氟哌酸(Norfloxacin)作对照,观察两药在疗效、疗程和不良反应上的差异。
Yimengdian is an acetamide derivative used to control acute nonspecific and chronic diarrhea. It is an agonist of the opioid receptors in the intestinal wall and can prevent the release of acetylcholine and prostaglandin, thereby inhibiting peristalsis and prolonging the retention of the contents time. Easy to stop can increase the anal sphincter tension, it can inhibit fecal incontinence and urgency. Norfloxacin is currently clinically used to treat diarrhea, one of the drugs. It stops diarrhea by reducing the susceptibility of bacterial toxins to intestinal flora by inhibiting susceptible flora. Yi Meng stopped in the early 70s began to apply to clinical, foreign reports of significant effect, there is still less systematic domestic research report. Norfloxacin was used as a control in this study to observe the difference in curative effect, course of treatment and adverse reaction between the two drugs.