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目的:探讨低体重儿及小胎盘与早发病型子痫前期(PE)及晚发病型PE发病的相关性。方法:随机选择于吉林大学白求恩第二医院妇产科诊治的早发病型PE患者46例及与之相匹配孕龄的健康孕妇42例,晚发病型PE患者47例及与之相匹配孕龄的健康孕妇44例,评估各组低体重儿和小胎盘的相关性及各组低体重儿和小胎盘合并率的差异性。结果:各组低体重儿与小胎盘的发生情况呈正相关,早发病型PE组低体重儿和小胎盘合并率均显著高于其他各组(P<0.05),晚发病型PE组低体重儿和小胎盘合并率与其健康对照组比较差异无统计学意义(P>0.05)。结论:小胎盘可能与早发病型PE及其低体重儿的发生相关,与晚发病型PE发生无关。
Objective: To investigate the relationship between low birth weight infants and small placenta and early onset preeclampsia (PE) and late onset PE. Methods: Forty-six patients with early-onset PE who were diagnosed and treated in Department of Obstetrics and Gynecology, the Second Hospital of Bethune, Jilin University, 42 healthy pregnant women with matched gestational ages, 47 pregnant women with late-onset PE and matched gestational age Healthy pregnant women in 44 cases to assess the correlation between the low-weight children and the small placenta in each group and the difference between the low-weight children and the small placenta merger rate in each group. Results: The incidence of small placenta in each group was positively correlated with the incidence of small placenta. The incidence of low birth weight infants and small placentas in early onset PE was significantly higher than that in other groups (P <0.05). The incidence of low birth weight infants There was no significant difference in the rate of merger between the small placenta and the small placenta compared with the healthy control group (P> 0.05). Conclusion: The placenta may be related to the occurrence of early-onset PE and its low-birth-weight infants, but not to the late-onset PE.