Near-atomic resolution structure of the largest known Ca2＋ channel： ryanodine receptor

• 作 者: WANG LiGuo
• 机 构: DepartmentofBiologicalStructure
• 出 处: 中国科学：生命科学英文版
• 发表日期: 2015年2期
• 关键词: 钙通道 高分辨率 受体 原子 结构 碱 哺乳动物 骨骼肌

<正>Ryanodine receptors(Ry Rs)are the major Ca2+channels that allow the release of Ca2+from the sarcoplasmic reticulum(SR)or the endoplasmic reticulum(ER).There are three known mammalian isoforms of Ry Rs:Ry R 1,2 and 3,which share 70%sequence identi