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目的建立孕11-14+6周正常胎儿MCA-PSV值,指导通过监测高危胎儿的MCA-PSV早期发现巴氏水肿胎,避免侵入性诊断方法引起的并发症。方法通过B超核算胎儿孕周,以我院112例定期产检孕妇为研究对象,夫妻双方之一地贫检查正常,测量11-14+6周的正常胎儿的MCA-PSV,对地贫筛查高危的胎儿抽取羊水行产前诊断。结果我院112例定期产检的孕妇正常MCA-PSV值随孕周的增加而增加,羊水诊断为巴氏水肿胎的MCA-PSV明显高于同孕周正常值的1.5MOM。结论孕早期MCA-PSV对预测胎儿а-地中海贫血有一定的指导意义。
Objective To establish MCA-PSV values of normal fetus during 11-14 + 6 weeks of gestation, and to guide the early detection of Papillary edema by MCA-PSV in high-risk fetus to avoid the complications caused by invasive diagnostic methods. Methods The fetal gestational age was calculated by B-mode ultrasonography. One hundred and twelve regular pregnant women in our hospital were enrolled in this study. Normal thalassemia was normalized in both spouses. MCA-PSV was measured in normal fetuses from 11 to 14 + 6 weeks, Prenatal diagnosis of high risk fetus fetus amniotic fluid. Results The normal MCA-PSV value of 112 pregnant women in our hospital increased with gestational weeks. The MCA-PSV of amniotic fluid diagnosed as Papillary edema was significantly higher than that of normal pregnant women (1.5MOM). Conclusion Early pregnancy MCA-PSV can predict fetal а-thalassemia has some guiding significance.