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High energy γ-ray can be used for nuclear waste transmutation by using the giant dipole resonance (GDR).The photonuclear reaction 197Au(γ,n) is known as a standard for studies on photoactivation experiments.The previous experiments on 197Au(γ,n) have been performed with bremsstrahlung,positron annihilation in flight or laser Compton scattering γ-ray.In this work,a new mono-energetic γ-ray source based on 13C(p,γ)14N reaction is used to measure the cross section of 197Au(γ,n) and the measured value is compared with the results obtained with other ways.