Insulin induces PKC-dependent proliferation of mesenteric vascular smooth muscle cells from hyperten

• 作 者: Xukai WANG Yan WANG Chenming Y
• 机 构: DepartmentofCardiovascularDisease
• 出 处: 老年心脏病学杂志：英文版
• 发表日期: 2006年2期
• 关键词: vascular smooth muscle cell PROTEIN KINASE C MITOGEN-ACTIVATED PROTEIN KINASE IN
• 基金项目: This work was supported by grants from the National Science Foundation of China (No. 30170384 and No. 30570764)

Background and objectives Proliferation of human vascular smooth muscle cells (VSMCs) induced by hyperinsulinemia is a very common clinical pathology. Extensive research has focused on PKC (Protein kinase C)-MAPK (mitogen-activated protein kinase)intracel