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患者男，５６岁。自幼面部起皮疹、瘙痒、流水，并渐扩展至躯干、四肢，间断治疗时轻时重。２岁后皮损局限于双小腿，反复发作并加重，皮损渐肥厚，表面粗糙及色素沉着。近２年右小腿皮损处化脓、破溃、疼痛，不能负重，形成足畸形。否认家族中有同样疾病。体检：身体瘦小...
Male patient, 56 years old. Since childhood, it has developed rashes, pruritus, and running water from the face, and has gradually spread to the trunk and limbs. It is light and heavy when treated intermittently. After 2 years of age, the skin lesions were confined to the double lower legs, which caused repeated episodes of aggravation and aggravated lesions. The lesions became hypertrophic, with rough surface and hyperpigmentation. In the past 2 years, the lesions of the right calf were suppurated, ulcerated, and painful. They could not bear weight and formed foot deformities. Deny the same disease in the family. Physical examination: thin body...