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β-内酰胺类抗生素由于具有高效、低毒、结构容易改造等特点,迄今为止一直处于极盛的发展时期。目前在国内,无论是广谱、长效、耐酸、耐酶的第三、第四代青霉素,头孢菌素,还是非典型的β-内酰胺抗生素象氧青霉烷类的克拉维酸、单环类的 Aztreo-nam等都在积极地开发和研制。随着各种各样新品种的不断问世,该类抗生素的主要副作用──过敏反应是否已得到解决则是人们极其关注的问题。本文仅就当前β-内酰胺类抗生素的质量和过敏反应关系的研究概况作一介绍,以供科研和生产部门在选择开发
β-lactam antibiotics has been in the flourishing period of development due to its characteristics of high efficiency, low toxicity and easy structural transformation. Currently in China, both broad-spectrum, long-lasting, acid and enzyme-resistant third and fourth generations of penicillins, cephalosporins, or atypical β-lactam antibiotics like oxybenzamides clavulanic acid, single Aztreo-nam ring are actively developing and research. With the advent of new varieties of all kinds, the main side effects of such antibiotics ─ ─ whether allergic reactions have been resolved are people are extremely concerned about the issue. This article only on the current quality of β-lactam antibiotics and allergic reactions Overview of the study made an introduction for the scientific research and production departments in the choice of development