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目的应用TCD观察依达拉奉联合奥扎格雷钠治疗急性脑梗死(ACI)与单用奥扎格雷钠血流动力学变化的差别。方法 80例住院患者随机分成治疗组(40例)和对照组(40例)。两组治疗前、治疗后14d应用TCD观察大脑中动脉(MCA)血流动力学变化,并进行对比研究。结果两组比较有显著性差异(P<0.01)。治疗组的血流动力学变化明显优于对照组。结论通过应用TCD,为指导临床治疗和评估疗效提供了有力的依据。
Objective To observe the difference of hemodynamics between edaravone and ozagrel sodium on acute cerebral infarction (ACI) and ozagrel sodium alone by TCD. Methods Eighty hospitalized patients were randomly divided into treatment group (40 cases) and control group (40 cases). Before treatment, 14 days after treatment, TCD was used to observe the changes of hemodynamics of middle cerebral artery (MCA). Results There was significant difference between the two groups (P <0.01). Hemodynamic changes in the treatment group were significantly better than those in the control group. Conclusion The application of TCD provides a strong basis for guiding the clinical treatment and evaluating the curative effect.