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目的分析新生儿血小板减少的临床特点及可能原因,探讨其预防和治疗措施。方法回顾性分析本院2008年1月～2009年7月诊断新生儿血小板减少症所有患儿的临床资料。结果早发型血小板减少患儿临床上多无特殊表现,预后较好;迟发型血小板减少症多发生于早产儿,小于胎龄儿,通常由于合并严重感染所致,病情严重,需要输注血小板来治疗。结论围产期有高危因素母亲,其新生儿出生后要常规监测血常规,对于宫内发育不良或低出生体质量儿生后一旦合并感染要警惕血小板减少,甚至DIC的发生。
Objective To analyze the clinical features and possible causes of neonatal thrombocytopenia and to explore its preventive and therapeutic measures. Methods The clinical data of all children with neonatal thrombocytopenia diagnosed in our hospital from January 2008 to July 2009 were analyzed retrospectively. Results Early onset thrombocytopenia in children with no special clinical manifestations, the prognosis is good; delayed thrombocytopenia occurred in premature children, less than gestational age children, usually due to severe combined infection, the condition is serious, the need for transfusion of platelets treatment. CONCLUSIONS: Mothers with high risk factors during perinatal period should be routinely monitored for blood routine after birth, and vigilance should be given to thrombocytopenia or even DIC in children with intrauterine growth retardation or low birth weight.