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目的:评价头孢哌酮与阿奇霉素联用治疗小儿获得性肺炎的临床疗效。方法:选取2012年3月—2014年5月间接受治疗的小儿获得性肺炎患儿76例,将其随机分为治疗组(n=38)和对照组(n=38);对照组患者给予阿奇霉素治疗,治疗组患者给予头孢哌酮与阿奇霉素联用治疗;分析和比较两组患儿的临床疗效、药物不良反应的发生情况和临床症状改善时间。结果:治疗组患儿治疗后的临床总有效率为89.47%,明显高于对照组为68.42%(P<0.05)以及不良反应发生率为5.26%,明显低于对照组为21.05%(P<0.05);治疗组患儿的发热消失时间、血常规恢复正常时间等明显优于对照组(P<0.05)。结论:头孢哌酮与阿奇霉素联用治疗小儿获得性肺炎可显著改善患儿的临床症状。
Objective: To evaluate the clinical efficacy of cefoperazone and azithromycin in the treatment of children with acquired pneumonia. Methods: A total of 76 children with infantile acquired pneumonia were selected from March 2012 to May 2014 and were randomly divided into treatment group (n = 38) and control group (n = 38). Patients in control group Azithromycin treatment, treatment group patients given cefoperazone and azithromycin combined treatment; analysis and comparison of two groups of children’s clinical efficacy, adverse drug reactions and clinical symptoms to improve the time. Results: The total effective rate of the treatment group was 89.47%, significantly higher than that of the control group (68.42%, P <0.05), and the incidence of adverse reactions was 5.26%, which was significantly lower than that of the control group (21.05%, P < 0.05). The disappearance of fever and normal blood routine in the treatment group were significantly better than those in the control group (P <0.05). Conclusion: The combination of cefoperazone and azithromycin in children with acquired pneumonia can significantly improve the clinical symptoms of children.