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目的了解桐庐地区原发性高血压患者的药物治疗状况。方法采用自制的《原发性高血压患者用药情况调查表》,对2 091例患者进行问卷调查,并进行12个月随访。结果农村和城镇高血压患者的抗高血压药物选择存在用药差别。所有患者单一用药比例为83.45%,农村和城镇患者的单一用药比例分别为89.64%和75.62%,2者差异具有统计学意义(P<0.05)。农村和城镇患者的用药不依从分别为24.14%和18.74%,2者差异具有统计学意义(P<0.05)。所有患者用药不合理占21.76%,血压达标率为50.31%;通过用药干预不合理率下降为7.13%,血压达标率为63.46%。血压达标率因患者参保医疗保险险种、用药依从性、用药合理性等因素不同而不同,差异均具有统计学意义(P<0.05)。单一用药和联合用药的患者之间血压达标率差异无统计学意义(P>0.05)。结论对高血压患者要进一步强调用药的合理性和用药依从性,以进一步提高血压达标率,减少并发症的发生。
Objective To understand the medical treatment of patients with essential hypertension in Tonglu area. Methods A self-made Questionnaire on the Use of Drugs in Patients with Essential Hypertension was conducted, and 2191 patients were surveyed and followed up for 12 months. Results There was a difference in drug use among antihypertensive drugs in rural and urban hypertensive patients. The proportion of single drug use in all patients was 83.45%. The single drug use rates in rural and urban patients were 89.64% and 75.62% respectively, with significant difference between the two groups (P <0.05). Inpatients in rural and urban areas did not comply with the medication, respectively, 24.14% and 18.74%, the difference between the two was statistically significant (P <0.05). All patients irrational medication accounted for 21.76%, blood pressure compliance rate was 50.31%; through medication intervention unreasonable rate dropped to 7.13%, blood pressure compliance rate was 63.46%. Blood pressure compliance rate due to the patient insured health insurance coverage, medication compliance, medication rationality and other factors vary, the differences were statistically significant (P <0.05). There was no significant difference in the compliance rate of blood pressure between single and combined patients (P> 0.05). Conclusion To further emphasize the rationality of medication and drug compliance in patients with hypertension to further improve the blood pressure compliance rate and reduce the incidence of complications.