论文部分内容阅读
目的 对重庆市艾滋病病毒感染者/艾滋病病人(HIV/AIDS)进行分子流行病学调查,为重庆市乃至全国的艾滋病预防控制工作提供有价值的资料。方法 传统流行病学与分子流行病学方法相结合,对重庆市HIV/AIDS的疫情特征进行分析,对重庆市HIV毒株作基因序列分析,总结其传播途径与亚型之间的关系,分析不同亚型在重庆市流行的时间及变异程度,并提出预防控制工作重点。结果 目前重庆市HIV感染率达11.7/10万,女性感染者比例高于全国平均水平;重庆市流行毒株有B’、C、E、G4种亚型,C亚型占优势,G亚型为全国首次发现。结论 重庆市艾滋病流行形势严峻,迫切需要深入开展研究,并在高危人群中开展行为干预措施。
Objective To investigate the molecular epidemiology of HIV / AIDS in Chongqing and provide valuable information for AIDS prevention and control in Chongqing and the whole country. Methods Traditional epidemiology and molecular epidemiological methods were combined to analyze the epidemic characteristics of HIV / AIDS in Chongqing. The sequences of HIV strains in Chongqing were analyzed by sequence analysis, and the relationship between their transmission and subtypes was analyzed. Different subtypes in Chongqing popular time and degree of variation, and put prevention and control priorities. Results HIV prevalence in Chongqing was 11.7 / 100,000 at present, and the proportion of female infected persons was higher than the national average. There were 4 subtypes of B ’, C, E, and G among the endemic strains in Chongqing, with C subtype dominant and G subtype For the first time found in the country. Conclusions The AIDS epidemic in Chongqing is in dire situation and there is an urgent need to carry out research in depth and conduct behavioral interventions in high-risk groups.