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应用激光作为物理诱生剂照射肿瘤患者脾区，观察其对人体内源性白细胞介素－２（ＩＬ－２）与ＮＫ细胞的作用。临床实验中，用我们自已研制的波长８３０ｎｍ、功率２０ｍＷ的半导体激光免疫治疗仪对肿瘤患者进行脾区照射两个疗程；在实施激光照射治疗前后均抽血，做ＩＬ－２活性和ＮＫ值测定。结果：经激光照射治疗后其ＩＬ－２活性为２１±５（Ｕ／ｍｌ）、ＮＫ值为８．３±５，与治疗前的１６±７（Ｕ／ｍｌ）及５．６±３相比有显著性差异。结果：提示激光照射肿瘤患者脾区，作为物理诱生剂可显著增强ＩＬ－２的活性，并使其ＮＫ值明显增高且接近正常值，从而增强对肿瘤生长的抑制作用。
The laser was used as a physical inducer to irradiate the spleen area of tumor patients, and its effect on human endogenous interleukin-2 (IL-2) and NK cells was observed. In clinical trials, we used the self-developed semiconductor laser immunotherapy device with a wavelength of 830 nm and a power of 20 mW to perform two courses of radiation in the spleen region of tumor patients; blood was taken before and after the laser irradiation treatment, and IL-2 activity and NK value were measured. . Results: IL-2 activity was 21±5 (U/ml) and NK value was 8.3±5 after laser irradiation treatment, which was 16±7 (U/ml) and 5.6±3 phase before treatment. There are significant differences. RESULTS: The laser irradiation of the spleen area of the tumor patient as a physical inducer could significantly enhance the activity of IL-2 and increase its NK value close to the normal value, thereby enhancing the inhibition of tumor growth.