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目的探讨在2型糖尿病合并高尿酸血症患者中开展痛风知识教育的临床效果。方法选取2型糖尿病合并高尿酸血症患者118例,随机分为观察组、对照组各59例,对照组予糖尿病教育,观察组予糖尿病教育联合痛风知识教育,随访6个月。在随访前及结束时监测生化指标。结果随访6个月后,观察组与对照组相比,血尿酸水平(398.18μmol/L vs445.83μmol/L)、甘油三酯(1.64 mmol/l vs 2.16 mmol/L)、低密度总胆固醇(2.81 mmol/L vs 3.20 mmol/L)明显下降,高密度脂蛋白胆固醇(3.22 mmol/l vs 1.26 mmol/L)明显升高,差异均有统计学意义(P<0.05)。结论在2型糖尿病合并高尿酸血症患者中开展痛风知识教育,可以产生明显降低血尿酸水平的效果,从而改善代谢紊乱。
Objective To investigate the clinical effects of gout knowledge education in type 2 diabetes mellitus patients with hyperuricemia. Methods A total of 118 type 2 diabetic patients with hyperuricemia were randomly divided into observation group (59 cases) and control group (59 cases). The control group was given diabetes education and the observation group was given diabetes education combined with gout knowledge education. The patients were followed up for 6 months. Biochemical indicators were monitored before and at follow-up. Results After 6 months of follow-up, the levels of serum uric acid (398.18 μmol / L vs 445.83 μmol / L), triglyceride (1.64 mmol / L vs 2.16 mmol / L), low density total cholesterol 2.81 mmol / L vs 3.20 mmol / L), and high density lipoprotein cholesterol (3.22 mmol / l vs 1.26 mmol / L) was significantly higher than that of the control group (P <0.05). Conclusion Gout knowledge education in patients with type 2 diabetes mellitus and hyperuricemia can produce a significant effect of lowering serum uric acid levels, thereby improving metabolic disorders.