早期补钙防治窒息新生儿继发性呼吸暂停的临床观察

• 作 者: 许文波 周丽
• 机 构: 广西壮族自治区防城港市第一人民医院儿科,
• 出 处: 中国妇幼保健
• 发表日期: 2012年33期
• 关键词: 继发性呼吸暂停 钙剂 防治 窒息 新生儿

目的:探讨早期补钙对窒息新生儿继发性呼吸暂停的防治作用,防止呼吸衰竭发生。方法:窒息新生儿78例,随机分为试验组39例和对照组39例,对照组予常规治疗,试验组在此基础上,加用10%葡萄糖酸钙治疗,2 ml/(kg·次),加等量5%葡萄糖稀释后缓慢静脉注射(1 ml/min),第1天,1次/8 h,第2天,1次/12 h,第3天,1次/24 h,3天为1个疗程,可重复使用。观察两组呼吸暂停、呼吸衰竭症状出现、缓解及消失情况。结果:试验组呼吸暂停控制时间、平均机械通气时间、住院时间、住院费用等均少于对照组,差异均有统计学意义(P<0.05)。结论:早期补钙对防治窒息新生儿继发性呼吸暂停有良好的效果,无严重不良反应,明显防止呼吸衰竭的发生。

Objective: To investigate the prevention and treatment of early calcium supplementation on secondary apnea in asphyxia neonates to prevent respiratory failure. Methods: 78 neonates with asphyxia were randomly divided into experimental group (n = 39) and control group (n = 39). The control group was given conventional treatment. On the basis of this, the experimental group was treated with 10% calcium gluconate, ), Diluted with equal volume of 5% glucose (1 ml / min), 1 day, 1 time / 8 hours, 2 days, 1 time / 12 hours, 3 days, 1 time / 24 hours, 3 days for a course of treatment, can be reused. Observe the two groups of apnea, respiratory failure symptoms appear, alleviate and disappear. Results: The control group had less apnea control time, mean duration of mechanical ventilation, hospitalization time and hospitalization cost than the control group (P <0.05). Conclusion: Early calcium supplementation has a good effect on the prevention and treatment of asphyxia neonatorum secondary apnea, without serious adverse reactions, and obviously prevent the occurrence of respiratory failure.