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应用放免法测定了７４例肺癌和７６例良性肺病患者血清（Ｓ）和支气管肺泡灌洗液（ＢＡＬＦ）中癌胚抗原（ＣＥＡ）及透明质酸（ＨＡ），同时测定了５８例健康人Ｓ－ＨＡ。结果显示：肺癌患者Ｓ－ＣＥＡ极显著高于良性肺病患者（Ｐ＜０．００１），肺癌患者Ｓ－ＨＡ极显著高于健康人和良性肺病患者（Ｐ均＜０．００１）。肺癌患侧ＢＡＬＦ－ＣＥＡ和ＢＡＬＦ－ＨＡ极显著高于肺癌健侧、良性肺病患侧和健侧（Ｐ＜０．００１或Ｐ＜０．００２）。根据各项指标在肺癌时的阳性率，选用Ｓ－ＣＥＡ、ＢＡＬＦ－ＣＥＡ和ＢＡＬＦ－ＨＡ作为诊断指标，当３项阳性时对肺癌诊断的敏感性为５３％，特异性为９７％、阳性预示值为９５％，用性预示值为７６％，准确性为７２％。
Serum (S) and CEA and HA in 74 cases of lung cancer and 76 cases of benign lung diseases were measured by radioimmunoassay. 58 healthy individuals were also tested. -HA. The results showed that S-CEA was significantly higher in patients with lung cancer than in patients with benign lung disease (P<0.001), and S-HA in lung cancer patients was significantly higher than in healthy and benign lung patients (P<0.001). Lung cancer affected BALF-CEA and BALF-HA were significantly higher than those in lung cancer, benign lung disease and affected side (P<0.001 or P<0.002). According to the positive rate of each index in lung cancer, S-CEA, BALF-CEA, and BALF-HA were used as diagnostic indicators. When the three items were positive, the sensitivity for lung cancer diagnosis was 53%, specificity was 97%, and positive predictive value. The value is 95%, the use predictive value is 76%, and the accuracy is 72%.