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目的 了解成人接种乙型肝炎疫苗免疫的效果及持久性 ,探讨加强免疫接种的适时性。方法 采用单纯随机抽样方法 ,动态观察免疫人群抗 -HBs阳性率变化及HBsAg携带情况。 结果 免疫接种后 9年间观察人群抗 -HBs有效阳转率从 80 .4 9%逐年降至 2 1 .4 3% ;在免疫接种后第九年HBsAg阳性率达 2 .0 4 %。结论 成人接种乙型肝炎疫苗可获得良好的免疫效果 ,在免疫接种 5年后应适时开展加强免疫接种
Objective To understand the effect and persistence of hepatitis B vaccination in adults and to explore the timeliness of immunization. Methods A simple random sampling method was used to observe the positive rate of anti-HBs and the status of HBsAg carrier in immunized population. Results In the 9 years after immunization, the positive rate of anti-HBs in the observed population decreased from 80.49% to 21.3% year by year. The positive rate of HBsAg in the ninth year after immunization was 2.04%. Conclusion Hepatitis B vaccination can get a good immunization effect in adults, and should be boosted timely after 5 years of immunization