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目的:观察口服加巴喷丁联合神经妥乐平神经阻滞治疗带状疱疹后神经痛的疗效。方法:98例带状疱疹后神经痛患者随机分为A、B 2组,A组采用加巴喷丁加神经妥乐平神经阻滞(神经妥乐平3.6IU+维生素B12针1.0mg+2%利多卡因针5mL,用生理盐水稀释至20mL)。B组采用口服加巴喷丁加复方倍他米松神经阻滞(复方倍他米松3.5mg+维生素B12针1.0mg+2%利多卡因针5mL,用生理盐水稀释至20mL)分别行各疱疹分布区的神经干、神经根及皮下注射。以视觉模拟评分法(VAS)和疗效评定评价治疗效果。结果:两组治疗后与治疗前比较以及治疗后两组间比较,VAS评分均明显降低(P<0.01);两组患者的显效率分别为93.87%,75.51%(P<0.05)。结论:加巴喷丁联合神经妥乐平神经阻滞治疗带状疱疹后神经痛疗效确切而且安全。
Objective: To observe the efficacy of oral gabapentin combined with neurotropin blockade in the treatment of post-herpetic neuralgia. Methods: A total of 98 patients with postherpetic neuralgia were randomly divided into A and B 2 groups. A group was treated with gabapentin plus neurotropin block (neurotracerone 3.6 IU + vitamin B12 needle 1.0 mg + 2% lidocaine needle 5 mL , Diluted to 20 mL with saline). Group B received oral gabapentin plus compound betamethasone nerve block (compound betamethasone 3.5mg + vitamin B12 needle 1.0mg + 2% lidocaine needle 5mL, diluted with saline to 20mL), respectively, the distribution of the neural stem of herpes zoster , Nerve root and subcutaneous injection. Visual analogue scale (VAS) and efficacy evaluation were used to evaluate the therapeutic effect. Results: The VAS scores of both groups were significantly lower after treatment than before treatment and after treatment (P <0.01). The effective rates of the two groups were 93.87% and 75.51%, respectively (P <0.05). Conclusion: Gabapentin combined with neurotropin blockade is effective and safe in the treatment of post-herpetic neuralgia.