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目的探讨颅脑损伤相关因素与精神障碍发生的关联性。方法随机选择纳入某院2010年1月～2011年6月因意外事故或其他原因导致的颅脑损伤患者80例,40例患者为颅脑损伤后导致早期的精神障碍患者(精神障碍组),40例患者为颅脑损伤后未出现精神障碍的患者(对照组)。采用格拉斯哥昏迷评分(GCS)、SF-36量表和艾森克人格问卷(EPQ)对80例患者进行问卷调查,并比较两组患者以上调查内容的差异。结果是否有经济赔偿、两组患者入院时意识得分(CGS)、两组患者生命质量的躯体健康(PCS)、精神健康得分(MCS)和EPQ评分在精神障碍组与对照组差异有统计学意义(P﹤0.05)。非条件Logistic回归分析发现,患者GCS评分高于8分和EPQ评分小于25分能降低患者患精神障碍的可能性(P﹤0.001)。PCS和MCS评分越低,患者患精神障碍可能性越高,差异有统计学意义(P﹤0.001)。结论脑外伤所致精神障碍与损伤后昏迷程度有一定关联,同时与患者的人格特征密切联系。今后在对脑外伤患者治疗的过程中,不但要针对脑外伤本身进行有效的治疗,更应该从人格特征和认知的角度出发,开展相应的心理学干预。
Objective To explore the correlation between brain injury related factors and mental disorders. Methods Totally 80 patients with craniocerebral injury were included in a hospital randomly selected from January 2010 to June 2011 due to accidents or other causes. Forty patients were patients with mental disorders (mental disorders) after craniocerebral injury, Forty patients were patients who did not have mental disorders after craniocerebral injury (control group). Eighty patients were surveyed by Glasgow Coma Scale (GCS), SF-36 and EPQ, and the differences of the above two groups were compared. The results showed that there was no financial compensation. There were significant differences in consciousness score (CGS), quality of life (PCS), mental health score (MCS) and EPQ score between the two groups in mental disorders group and control group (P <0.05). Non-conditional logistic regression analysis found that patients with GCS score higher than 8 and EPQ score less than 25 can reduce the possibility of mental disorders (P <0.001). The lower the PCS and MCS scores, the higher the probability of having a mental disorder and the difference was statistically significant (P <0.001). Conclusion The mental disorders caused by traumatic brain injury have a certain relationship with the degree of post-traumatic coma. At the same time, they are closely linked with the personality traits of patients. In the future in the treatment of patients with traumatic brain injury, not only for the effective treatment of traumatic brain injury itself, but also from the perspective of personality traits and cognition, to carry out the corresponding psychological intervention.