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近年来由于化疗的进展,急性白血病的缓解率不断地提高,生存期在延长。但由于大多数化疗药物不能有效地透过血脑屏障,中枢神经系统白血病(脑白)的发病率有所增高,严重成胁患者的生命。为此,对脑白的预防、早期发现和治疗则极为重要。现将我院1974~1984年收治的263例白血病患者中并发中枢神经系统白血病的情况报告如下:临床资料本组263例白血病患者中并发中枢神经系统的21例(占7.9%),其中男14例,女7例。在263例中 ALL(急性淋巴细胞性白血病)85例,并发脑白者12例占14.1%,其中男8例,女4例,年龄14~40岁。ANLL(急非淋白血病包括急性粒细胞性白血病,急性单核细胞性白血病及其他急
In recent years due to the progress of chemotherapy, acute leukemia remission rate continued to improve, prolong survival. However, since most chemotherapeutic drugs can not effectively penetrate the blood-brain barrier, the incidence of central nervous system leukemia (LOH) is increased, seriously threatening the life of the patient. For this reason, prevention and early detection and treatment of white matter are extremely important. Now in our hospital from 1974 to 1984 admitted to the 263 cases of leukemia in patients with central nervous system leukemia are as follows: Clinical data of the group of 263 cases of leukemia in patients with central nervous system in 21 cases (7.9%), of which male 14 Cases, female 7 cases. In 263 cases of ALL (acute lymphoblastic leukemia) in 85 cases, 12 cases of complicated brain white accounted for 14.1%, including 8 males and 4 females, aged 14 to 40 years. ANLL (acute non-leukemias including acute myeloid leukemia, acute monocytic leukemia and other acute