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目的 :了解徐州市大肠杆菌O1 57∶H7感染性腹泻的流行情况及并发急性肾衰的临床表现。方法 :将 1999年收治的 14 7例大肠杆菌O1 57∶H7感染性腹泻并发急性肾衰的临床资料进行总结。结论 :1999年夏季 ,徐州市铜山县、丰县及与接壤的安徽萧县发生了大肠杆菌O1 57∶H7感染性腹泻的大规模爆发性流行 ,病人除以腹泻为主要表现外 ,还以急性肾衰、呼吸系统及中枢神经系统损害为特征。病情来势凶猛 ,病程进展迅速 ,预后严重 ,死亡率高达 80 %。由于菌株的变种 ,2 0 0 0年发病率明显下降
Objective: To understand the epidemic situation of Escherichia coli O1 57:H7 infectious diarrhea in Xuzhou City and the clinical manifestations of acute renal failure. Methods: The clinical data of 14 7 cases of Escherichia coli O1 57:H7 infectious diarrhea complicated with acute renal failure admitted in 1999 were summarized. Conclusion: In the summer of 1999, a large-scale outbreak of Escherichia coli O1 57: H7 infectious diarrhea occurred in Tongshan County, Feng County, Xuzhou City and the neighboring Xiaoxian County in Anhui Province. The patients were divided by diarrhea as the main manifestation, Renal failure, respiratory and central nervous system damage characterized. The situation is ferocious, rapid course of progress, the prognosis is serious, the mortality rate as high as 80%. Due to the variant of the strain, the incidence rate in 2000 decreased significantly