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自身免疫溶血性贫血(AIHA)是患者体内的变性红细胞作为抗原,刺激机体产生了抗自身红细胞的抗体,从而使红细胞破坏引起的溶血性贫血。红细胞自身抗体分温型与冷型,直接抗人球蛋白试验(directantiglobulin test,DAT)阳性为诊断温抗体型AIHA必备条件。但实际上,临床也可见到一类DAT阴性的
Autoimmune hemolytic anemia (AIHA) is the patient’s denatured erythrocytes as an antigen to stimulate the body to produce anti-red blood cell antibodies, so that red blood cell damage caused by hemolytic anemia. Erythrocyte autoantibody sub-type and cold type, direct antiglobulin test (direct antiglobulin test, DAT) positive for the diagnosis of warm antibody AIHA essential conditions. However, in fact, a class of DAT negative can be seen clinically