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1995年6月～1998年6月共收治细菌性痢疾117例。瑞贝克(Swibec)治疗组60例,诺氟沙星对照组57例,观察两组疗效,进行对比分析,报告如下。 1资料与方法 1.1诊断标准 ①有不洁饮食史;②有腹痛、腹泻、粘液血便、里急后重、发热等急性细菌性痢疾的临床表现;③大便常规异常;④大便培养有痢疾杆菌生长。 1.2病例选择 117例患者随机分为瑞贝克(Swibec)治疗组与诺氟沙星对照组,治疗组60例,对照组57例。经培养共检出痢疾杆菌117株,其中福氏痢疾杆菌96株(82.0％),宋内氏痢疾杆菌19例(16.2％),志贺氏痢疾杆菌2株(1.8％)。两组在年龄、性别、临床表现、程度等方面,经t检验和X~2检验无显著性差异(P>0.05)。
From June 1995 to June 1998, 117 cases of bacterial dysentery were admitted. 60 patients in the treatment group of Swibec and 57 patients in the norfloxacin control group. The curative effect of the two groups were observed and compared as follows. 1 Materials and Methods 1.1 diagnostic criteria ① history of unclean diet; ② abdominal pain, diarrhea, mucus bloody stools, tenesmus, fever and other acute bacterial dysentery clinical manifestations; ③ stool abnormalities; ④ stool culture dysentery bacilli growth. 1.2 Case Selection 117 patients were randomly divided into Swibec treatment group and norfloxacin control group, 60 cases in the treatment group and 57 cases in the control group. A total of 117 strains of dysentery bacilli were detected, of which 96 (82.0%) were Shigella dysenteriae, 19 (16.2%) were Shigella dysenteriae and 2 (1.8%) were Shigella dysenteriae. Two groups in terms of age, gender, clinical manifestations, extent and so on, by t test and X ~ 2 test no significant difference (P> 0.05).