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为研究无机汞的男（雄）性生殖毒性，对职业性接触金属汞作业的男工进行了生殖功能流行病学调查，并通过动物实验研究了汞对雄性动物生殖腺的影响。结果显示：职业接触汞男工的性欲减退发生率显著高于对照组（Ｐ＜０．０１）；接汞男工妻子的先兆流产发生率显著高于对照组（Ｐ＜０．０５）；未发现对妊娠结局有明显的影响；未观察到现有接汞水平对子代存有不良影响。汞对雄性动物生殖腺有明显的损伤作用。病理检查可见：染毒组雄鼠睾丸点灶性曲细精管上皮排列紊乱、细胞脱落、成熟精子减少；电镜下可见：高剂量组精子细胞胞浆中脂质颗粒增多，表明精子有退行性改变。因此，汞对男（雄）性生殖危害的作用应进一步研究。
In order to study male and female reproductive toxicity of inorganic mercury, male workers in occupational exposure to metal-mercury were investigated for reproductive function and the effects of mercury on the gonads of male animals were studied through animal experiments. The results showed that the occupational mercury exposure was significantly higher in the male workers than in the control group (P <0.01). The incidence of threatened abortion was significantly higher in the mercury male workers than in the control group (P <0.05). It was found to have a significant effect on pregnancy outcome; no evidence of adverse effects of current available mercury levels on offspring was observed. Mercury on the male gonads obvious damage. Pathological examination showed that the epithelium of the focal seminiferous tubules in the testis of the exposed rats were disordered, the cells were shed and the mature spermatozoa were reduced. Electron microscopy showed that the number of lipid granules in the cytoplasm increased in the sperm cells in the high dose group, indicating that the sperm degenerated change. Therefore, the role of mercury in male (male) sexual reproduction should be further studied.