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目的:观察阿伦膦酸钠治疗绝经后骨质疏松症(PMO)的疗效。方法:选100例PMO应用阿伦膦酸钠治疗12个月,于治疗前后测定骨转换指标及骨密度。结果:阿伦膦酸钠治疗后患者骨密度较前升高(P<0.01),尿NTX及ALP较前降低(P<0.05)。结论:阿伦膦酸钠对PMO的治疗有效。
Objective: To observe the efficacy of alendronate in the treatment of postmenopausal osteoporosis (PMO). Methods: One hundred cases of PMO were treated with alendronate for 12 months. The indexes of bone turnover and bone mineral density were measured before and after treatment. Results: The bone mineral density of patients treated with alendronate was significantly higher than before (P <0.01), while NTX and ALP of urine were lower than before (P <0.05). Conclusion: Alendronate is effective in the treatment of PMO.