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为掌握南宁市新生儿腹泻病原谱及医院内感染的特点，有效地控制新生儿腹泻的发生，建立快速简便、稳定实用的诊断方法，作者于１９８８～１９９３年对南宁市５家医院７８７例新生儿腹泻患者进行了病原学检测及耐药性监测，检出各类病原体２６１例，检出率３３．２％，病原性大肠菌为主要致泻菌，占总检出率的５３．２％，揭示病原性大肠菌是南宁市新生儿腹泻的主要病原。医院内感染以沙门氏菌和致病性大肠菌为主。同时对５种常见的致泻病原作了药敏试验观察，均呈现出不同程度的耐药情况，提示新生儿腹泻病原菌耐药现象日趋严重，这可能与医院不合理使用抗生素有关，文中对此作了分析与讨论。
In order to grasp the characteristics of neonatal diarrhea pathogenic spectrum and nosocomial infection in Nanning and to effectively control the occurrence of neonatal diarrhea, a rapid and simple, stable and practical diagnostic method was established. The author studied 787 freshmen from 5 hospitals in Nanning from 1988 to 1993 Pediatric diarrhea patients were tested for pathogenicity and drug resistance, 261 cases of various pathogens were detected, the detection rate was 33.2%, pathogenic coliforms as the main diarrhea bacteria, accounting for 53.2% , Revealing pathogenic coliforms is the main cause of neonatal diarrhea in Nanning City. Nosocomial infections are mainly Salmonella and pathogenic coliforms. At the same time, five kinds of common diarrheal pathogens were tested by drug susceptibility test, showing different degrees of resistance, suggesting that the pathogens of neonatal diarrhea become more and more serious, which may be related to unreasonable use of antibiotics in hospitals. Made analysis and discussion.