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研究目的探讨血红蛋白（Hb）和红细胞原卟啉（EP）水平与海拔高度的关系研究方法青海省贵南县及玛多县海拔高度分别为3200米和4300米。选该两县7岁～14岁在校健康中小学学生各122人，用滤纸片高铁氰化法检测血红蛋白，用滤纸片荧光分光光度计法检测红细胞原卟啉，用t检验和配对t检验进行统计学处理。结果贵南县和玛多县7岁～14岁建康儿童Hb分别为133．6±10．1，152．8±14．0g／L（t＝12．31，P＜0．001），EP分别为320．7±114．9，347．8±123．6μg／L（t＝1．77，P＞0．05），EP／Hb分别为2．4±0．9，2．3±0．8（t＝1．12，P＞0．05）。配对t检验显示，Hb、EP、EP／Hb男女之间无显著性差异（P＞0．05）结论随海拔高度增加，7岁～14岁儿童Hb及EP水平显著升高，无性别差异。
Objective To explore the relationship between hemoglobin (Hb) and erythrocyte protoporphyrin (EP) level and altitude. Methods The altitude of Guinan County and Maduo County in Qinghai Province are respectively 3,200 and 4,300 meters. Select the two counties 7 years old to 14 years old healthy primary and secondary school students in 122 each with a filter paper high ferricyanide hemoglobin detection method using filter paper fluorescence spectrophotometer detection of erythrocyte protoporphyrin t test and paired t test Statistical analysis. Results Hb was 133.6 ± 10.1 and 152.8 ± 14.0 g / L (t = 12.31, P <0.001) in Jiankang children aged from 7 to 14 years in Guinan and Maduo counties respectively, EP were 320.7 ± 114.9,347.8 ± 123.6μg / L (t = 1.77, P> 0.05), EP / Hb was 2.4 ± 0.9,2.3 ± 0.8 (t = 1.12, P> 0.05). Paired t-test showed no significant difference between Hb, EP, EP / Hb men and women (P> 0.05) .Conclusion Hb and EP levels in children aged 7-14 years old were significantly increased with altitude increasing, with no gender differences.