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目的通过对男性患者精子质量分析,精浆抗精子抗体(antisperm antibodyAsAb)检测,分析精浆中抗精子抗体IgA与精子质量各项参数的相关性的。方法采用禁欲3-7天不育症患者的精液标本检测精子质量,进行精浆抗精子抗体检测.后对检测抗精子抗体阳性抗精子抗体阴性患者分组进行精子质量参数的统计学分析。结果280例不育男性抗精子抗体阳性率为15.35%,其精子的密度/活率活动度/均低于阴性组,两组间存在显著差异(P<0.01)。结论精浆抗精子抗体IgA与精子密度、活率、精子活力关系密切是男性不育的主要原因之一。
Objective To analyze the correlation between sperm quality and seminal plasma IgA in seminal plasma by using antisperm antibodyAsAb. Methods Semen samples of 3-7 day infertility patients with abstinence were tested for sperm quality and seminal plasma anti-sperm antibodies were detected, and the sperm quality parameters of the patients with negative anti-sperm antibody positive anti-sperm antibody were analyzed. Results The positive rate of antisperm antibody in 280 infertile men was 15.35%. The sperm densities / activities were lower than those in the negative group (P <0.01). Conclusion Sperm anti-sperm IgA is closely related to sperm density, viability, sperm motility and is one of the main causes of male infertility.