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目的观察硝酸舍他康唑软膏对股癣的疗效及安全性。方法 57例患者分为治疗组和对照组。治疗组用2%硝酸舍他康唑乳膏外涂患处患处,每天1次。对照组用硝酸咪康唑乳膏外涂患处,每天1次。治疗前及治疗后1周、4周分别真菌直接镜检,每次就诊记录皮疹及自觉症状情况及变化。结果所有患者经治疗4周后观察疗效,治疗组治愈率(84.4%)优于对照组的(56.0%,P﹤0.05)。结论硝酸舍他康唑软膏治疗股癣疗效优于硝酸咪康唑乳膏,且安全可靠,无明显不良反应。
Objective To observe the efficacy and safety of sertaconazole nitrate ointment on jock itch. Methods 57 patients were divided into treatment group and control group. Treatment group with 2% sertaconazole nitrate cream applied to the affected area, once daily. The control group was treated with miconazole nitrate cream applied to the affected area once daily. Before treatment and after treatment for 1 week, 4 weeks respectively fungi direct microscopic examination, each visit records rash and subjective symptoms and changes. Results All patients were observed after 4 weeks of treatment. The cure rate in the treatment group (84.4%) was better than that in the control group (56.0%, P <0.05). Conclusion The sertaconazole nitrate ointment is superior to miconazole nitrate cream in the treatment of tinea corporis and is safe and reliable with no obvious adverse reactions.