论文部分内容阅读
胸腔积液(PE)是许多疾病的临床表现之一,PE按其发生机制可分为渗出液和漏出液。漏出液往往由于心衰、低蛋白血症、肾衰等引起,病因较明确,对于渗出液而言,临床上多见于结核性和癌性,两者的鉴别对指导治疗是非常重要的,本文就上述问题作一综述。 1 糖链抗原 1.1 CA_(242)是1983年Linahalm等从结肠癌细胞经杂交瘤技术获得的单克隆抗体C_(242)发展而发。CA_(242)是比较理想的肿瘤标志物,对多种肿瘤具有鉴别诊断价值,有报道78例胸水检测癌性胸水CA_(242)含量明显高于结核性胸水(P<0.001),敏感性为69.2％,特异性100％,准确度79.5％。朱旭等检测了52例良恶性胸水中CA_(242)水平也有类
Pleural effusion (PE) is one of the clinical manifestations of many diseases, PE, according to its mechanism can be divided into exudate and leakage. Leakage fluid is often due to heart failure, hypoproteinemia, renal failure caused by the more clear cause, for the exudate, the clinical more common in tuberculosis and cancer, the distinction between the two is very important to guide the treatment, This article reviews the above issues. 1 Sugar Chain Antigen 1.1 CA_ (242) was developed in 1983 by Linahalm et al., A monoclonal antibody C_ (242) derived from colon cancer cells by the hybridoma technique. CA 242 is an ideal tumor marker with differential diagnosis value for many kinds of tumors. It has been reported that CA_ (242) in pleural fluid of 78 patients with pleural effusion was significantly higher than that of tuberculous pleural effusion (P <0.001), and the sensitivity was 69.2%, specificity 100%, accuracy 79.5%. Zhu Xu et al detected 52 cases of benign and malignant pleural effusion CA_ (242) levels are also class