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目的探讨纳洛酮在抢救海洛因中毒中的疗效。方法回顾分析20例急性海洛因中毒临床病历资料。结果静脉注射纳洛酮0.4～0.8 mg后(3.6±1.2)min产生明显作用,R、HR、SBP均增高,用药前后有统计学差异(P<0.05)。结论纳洛酮能拮抗阿片类物质引起的呼吸抑制,使血压升高,心率增快。
Objective To investigate the efficacy of naloxone in the treatment of heroin poisoning. Methods The clinical records of 20 cases of acute heroin poisoning were retrospectively analyzed. Results Naloxone 0.4 ~ 0.8 mg intravenously (3.6 ± 1.2) min had a significant effect, R, HR, SBP were increased, before and after treatment with a statistically significant difference (P <0.05). Conclusion Naloxone can antagonize the opioid respiratory depression, blood pressure, heart rate faster.