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静脉滴注(静滴)是临床上广泛使用的一种给药方法,只要选取适当的静滴速率,就能使稳态血药浓度等于治疗所需要的最佳有效血药浓度c_b,但对于半衰期较长的药物,静滴后血药浓度达到稳态值需很长时间,为了克服这一缺点,有同时快速静脉注射(静注)的方法。这一方法,对于一室模型药物,适当地选择静注剂量x_o和静滴速率k_o,可以使血药浓度在用药期间保持任一恒定值,从而有可能使血药浓度在用药期间保持最佳有效血药
Intravenous infusion (intravenous drip) is widely used in clinical practice, as long as the appropriate infusion rate, can make the steady-state plasma concentration equal to the best effective plasma concentration required for treatment c_b, but for Long half-life of the drug, blood concentration after intravenous infusion to a steady state value takes a long time, in order to overcome this shortcoming, there are rapid intravenous (intravenous) method. In this method, for a one-compartment model drug, a suitable choice of the intravenous dose x_o and the intravenous infusion rate k_o allows the plasma concentration to be kept at any constant value during the administration, making it possible to keep the plasma concentration optimal during the administration Effective blood medicine