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内镜下逆行胰胆管造影术(ERCP)已成为目前消化系统疾病的重要临床诊断及治疗手段,但其术后胰腺炎(post-ERCP pancreatitis,PEP)等并发症的高发病率大大限制了临床应用,亦给患者生命带来了严重威胁。预防PEP成为ERCP相关研究的热点。药物预防PEP的现状不容乐观,目前尚无一种药物可有效预防PEP;然而,非药物措施,如胰管支架植入术、导丝引导插管等在PEP的预防中显示出良好的效果,为PEP的有效预防带来了新希望。本文就非药物预防措施预防PEP的研究现状作一综述。
Endoscopic retrograde cholangiopancreatography (ERCP) has become an important clinical diagnosis and treatment of digestive diseases, but the high incidence of postoperative complications such as post-ERCP pancreatitis (PEP) has greatly limited the clinical Application, but also to the patient’s life posed a serious threat. Prevention of PEP has become a hot topic in ERCP research. However, there are no drugs that can effectively prevent PEP. However, non-drug measures, such as pancreatic duct stenting and guide wire guide catheters, have shown good results in the prevention of PEP, Bring new hope for the effective prevention of PEP. This article reviews the current status of non-drug preventive measures to prevent PEP.