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本文用ELISA法检测日本血吸虫病患者的特异性IgE抗体。50例急性、14例慢性患者血清均为阳性;40例晚期血吸虫病患者特异性IgE抗体的阳性率仅27.5%;77例健康献血员的假阳性率为1.2%。提示检测特异性IgE抗体有较高的敏感性和特异性。16例经吡喹酮治疗后3个月,12例粪检阴性者中7例IgE抗体转为阴性,4例粪检仍阳性者IgE抗体均为阳性:该16例的IgG抗体均为阳性。
In this paper, ELISA method for detection of schistosomiasis japonica specific IgE antibodies. 50 cases of acute, 14 cases of chronic serum were positive; 40 cases of advanced schistosomiasis patients with specific IgE antibody positive rate was only 27.5%; 77 healthy blood donors false positive rate was 1.2%. Prompt detection of specific IgE antibodies have a higher sensitivity and specificity. Of the 16 patients treated with praziquantel, 7 of the 12 patients with negative stool tests turned negative and 4 of them were still positive with IgE antibodies. All 16 patients were positive for IgG antibodies.