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目的:探究活血化瘀中药在奥沙利铂化疗中辅助治疗应用价值。方法:随机选取重庆市璧山区中医院2012年3月至2015年4月收治入院的接受奥沙利铂化疗的患者64例,按照随机双盲法原则将其分成观察组和对照组,各32例,对照组在奥沙利铂化疗的基础上予以常规护理,观察组在对照组的基础上予以活血化瘀中药治疗,主要观察两组患者周围神经毒性发生情况。结果:观察组周围神经毒性发生率显著低于对照组,比较差异具有统计学意义(P<0.05),且治疗后,观察组卡式评分标准(KPS)评分改善效果明显优于对照组,差异具有统计学意义(P<0.05)。结论:活血化瘀中药在辅助用于奥沙利铂化疗中,能够有效降低周围神经毒性发生率。
Objective: To explore the value of adjuvant therapy for promoting blood circulation and removing blood stasis in the chemotherapy of oxaliplatin. Methods: Sixty-four patients admitted to Bishan District Hospital of Traditional Chinese Medicine in Chongqing from March 2012 to April 2015 were randomly divided into observation group and control group according to the randomized double-blind principle For example, the control group was given routine nursing care based on the oxaliplatin chemotherapy. The observation group was treated with traditional Chinese medicine on the basis of the control group, mainly to observe the peripheral neurotoxicity in the two groups. Results: The incidence of neurotoxicity around the observation group was significantly lower than that of the control group (P <0.05). After treatment, the KPS score of the observation group was significantly better than that of the control group Statistically significant (P <0.05). Conclusion: Chinese herbs for promoting blood circulation and removing blood stasis can effectively reduce the incidence of peripheral neurotoxicity in the adjuvant chemotherapy with oxaliplatin.