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目的了解上海某地区泌尿生殖道衣原体属和支原体属与脲支原体属的感染情况及耐药情况。方法对1464例泌尿生殖道感染者标本进行衣原体属抗原鉴定、支原体属和脲支原体属培养、鉴定和药敏试验。结果衣原体属、支原体属、脲支原体属总检出率为49.3%,其中单纯沙眼衣原体(Ct)阳性率6.4%,单纯解脲脲支原体(Uu)为28.7%,人支原体(Mh)为2.3%,Uu+Mh为7.9%;衣原体属的感染率低于支原体属和脲支原体属,女性衣原体属、支原体属、脲支原体属的感染率高于男性;支原体属对米诺环素和多西环素最敏感,Uu分别为96.4%和95.5%,Mh分别为66.7%和69.7%,Ct+Uu分别为92.7%和90.2%,Uu+Mh分别为80.9%和79.1%;耐药性最高的抗菌药物为环丙沙星、诺氟沙星和大观霉素。结论该地区支原体属和脲支原体属感染率要高于衣原体属感染率,且以Uu为主,女性高于男性;与Uu相比,Mh和Uu+Mh感染后抗菌药物的敏感率有下降的趋势,耐药性有升高的趋势,治疗泌尿生殖道支原体属感染的首选抗菌药物为四环素类米诺环素和多西环素。
Objective To understand the prevalence and drug resistance of urogenital genitalia, mycoplasma and ureaplasma genus in a certain area of Shanghai. Methods A total of 1464 cases of genitourinary tract infection were identified as Chlamydia antigen, Mycoplasma and Ureaplasma urealyticum were cultured, identified and susceptibility test. Results The total positive rate of Chlamydia, Mycoplasma and Ureaplasma was 49.3%. The positive rate of Ct was 6.4%, that of Uu was 28.7% and that of Mycoplasma hominis was 2.3% , And Uu + Mh was 7.9%. The prevalence of Chlamydia was lower than that of Mycoplasma and Ureaplasma. The prevalence of Chlamydia, Mycoplasma and Ureaplasma were higher in women than in men. Uu were 96.4% and 95.5% respectively, Mh was 66.7% and 69.7% respectively, Ct + Uu was 92.7% and 90.2% respectively, and Uu + Mh was 80.9% and 79.1% The drugs are ciprofloxacin, norfloxacin and spectinomycin. Conclusions The prevalence of Mycoplasma and Ureaplasma in this area is higher than that of Chlamydia, and mainly Uu, while the female is higher than the male. Compared with Uu, the susceptibility of antimicrobial drugs after Mh and Uu + Mh infection is decreased Trend, resistance has increased trend, the treatment of genitourinary tract mycoplasma infection preferred antibacterial drugs tetracycline minocycline and doxycycline.