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隐孢子虫是一种原虫,能引起许多动物的胃肠炎,是儿童胃肠炎的常见原因。在免疫机能正常的儿童中,隐孢子虫一般只引起急性自限性疾病;而在免疫损害的儿童中隐孢子虫感染可引起持续几个月甚至几年严重的、危及生命的腹泻。至今对隐孢子虫感染尚无确切的有效疗法。作者报道一名10岁男孩,被诊断为急性前B细胞白血病,经1个月的氨甲喋呤、氢化可的松等药物治疗后,病情缓解。经6个月L-天门冬酰胺酶和大剂量的氨甲喋呤巩
Cryptosporidium is a protozoa that causes gastroenteritis in many animals and is a common cause of gastroenteritis in children. Cryptosporidiosis usually causes acute self-limiting disease in immunocompetent children; and Cryptosporidium infection in immunocompromised children can cause serious, life-threatening diarrhea lasting months or even years. Cryptosporidium infection so far there is no exact and effective treatment. The authors report that a 10-year-old boy who had been diagnosed with acute pre-B cell leukemia was relieved after 1 month of methotrexate, hydrocortisone and other medications. After 6 months L-asparaginase and large doses of methotrexate Gong