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目的:观察健脾益气降浊法治疗高脂血症的降脂疗效。方法:将100例患者随机分对照组和治疗组各50例,对照组采用辛伐他汀口服治疗,治疗组在对照组治疗基础上加服健脾益气降浊方药。观察临床疗效、血脂水平及血液流变学指标变化情况。结果:降脂疗效总有效率治疗组为84.0%,对照组为80.0%,2组比较,差异无显著性意义(P>0.05)。治疗后2组血脂及载脂蛋白各指标均较治疗前明显改善,差异有显著性或非常显著性意义(P<0.05,P<0.01)。治疗组除总胆固醇外,其余7个指标与对照组治疗后比较,差异有显著性或非常显著性意义(P<0.05,P<0.01)。治疗后治疗组各血液流变学指标均较治疗前显著降低(P<0.01);与对照组治疗后比较,差异有非常显著性意义(P<0.01)。对照组各血液流变学指标治疗前后变化不明显,差异无显著性意义(P>0.05)。结论:健脾益气降浊法结合西药对高脂血症有较好的降脂效果,并能改善血流紊乱状态。
Objective: To observe the effect of lowering blood pressure on the treatment of hyperlipidemia with the method of invigorating the spleen and invigorating the qi and lowering blood pressure. Methods: 100 patients were randomly divided into control group and treatment group, 50 cases each. The control group was treated with simvastatin orally. The treatment group was given Jianpi Yiqi Jiangzhuo decoction on the basis of the control group. To observe the clinical efficacy, blood lipid levels and changes in hemorheology indicators. Results: The total effective rate of lipid-lowering therapy was 84.0% in the treatment group and 80.0% in the control group. There was no significant difference between the two groups (P> 0.05). After treatment, the indexes of blood lipids and apolipoproteins in two groups were significantly improved compared with before treatment, the difference was significant or very significant (P <0.05, P <0.01). In addition to the total cholesterol in the treatment group, the other seven indicators compared with the control group after treatment, the difference was significant or very significant (P <0.05, P <0.01). After treatment, the hemorrheological indexes of the treatment group were significantly lower than those before treatment (P <0.01). Compared with the control group, the differences were significant (P <0.01). There was no significant difference in the indexes of hemorheology before and after treatment in the control group (P> 0.05). Conclusion: The method of invigorating the spleen, invigorating the spleen and invigorating the health and lowering the turbid method combined with western medicine has better lipid lowering effect on hyperlipidemia and can improve the disturbance of blood flow.