茉莉酸介导的药用植物次生代谢转录调控（英文）

• 作 者: Sadia Afrin 黄景嘉 罗志勇
• 机 构: Molecular Biology Research Center, State Key Laboratory of Medical Genetics, School of Life Sciences
• 出 处: Science Bulletin
• 发表日期: 2015年12期
• 关键词: Jasmonic acid Medicinal plant Secondary metabolite Transcription factor
• 基金项目: supported by the National Natural Science Foundation of China(30470189,81071821,81250110086 and 81250110551);the Fundamental Research for the Central University of China(721500011);the Key Hunan Pro

Plants produce a wide spectrum of secondary metabolites that play critical roles in plant-environment interactions and against biotic and abiotic stresses.Moreover, many secondary metabolites have pharmaceutical efficacy for a wide range of diseases(cancer,malaria, etc.). Controlled transcription of biosynthetic genes is one of the major mechanisms regulating secondary metabolism in plants. Several transcription factor families such as MYC, MYB, WRKY and AP2/ERF have been found to be involved in the regulation of secondary metabolism in different medicinal plants. In addition, the biosynthesis and proper accumulation of secondary metabolites are also induced by signaling molecule jasmonic acid(JA). This review provides an insight into JA signaling pathway and JA-mediated transcriptional regulation of secondary metabolism(vinblastine, nicotine,artemisinin, taxol and ginsenoside) in a range of medicinal plant species.