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安乃近(Analgin)引起皮疹及粒细胞缺乏症在临床上常见,但引起小儿出血性坏死性肠炎则为罕见,本院自1987年以来收治2例,特报告如下: 例1:男,4岁,因发热服用安乃近半片(0.5g/片),当晚热未退又服2/3片,次日开始出现腹痛,2天后因腹痛、腹胀、呕吐及解果酱样大便而诊断为肠套叠收住我科。入院时查;T39℃、P120次/分,表情淡漠、脉搏细弱,心肺听诊(-)、腹胀,全腹压痛,肠鸣音减弱,腹部未扪及包块;白细胞21000,N87％、L13％;大便:暗红色粘液状,红细胞(+++),PC(+),潜血试验强阳性,诊断性穿刺有血性样液体,入院后考虑:1.绞窄性肠梗阻;2.中毒性休克。禁经食、胃肠减压及使用大剂量抗生素、补液、纠酸、
Analgin-induced rash and agranulocytosis are clinically common, but are rare in children with hemorrhagic necrotizing enterocolitis. Two cases have been treated in our hospital since 1987, and are reported as follows: Example 1: Male, 4 Year old, due to fever taking nearly half of tablets (0.5g / tablet), the heat did not return the next night and served 2/3, the next day began to appear abdominal pain, abdominal pain, bloating, vomiting and solution 2 days after the diagnosis of intestinal stool Nesting in my department. T39 ℃, P120 beats / min, apathy, pulse weakness, cardiopulmonary auscultation (-), abdominal distension, abdominal tenderness, bowel sounds weakened, abdomen not palpable mass; white blood cells 21000, N87%, L13% Stool: dark red mucus, erythrocytes (+++), PC (+), strong positive occult blood test, diagnostic puncture with bloody fluid, after admission, consider: 1. Stranded intestinal obstruction; 2. Toxic shock . Prohibition of food, gastrointestinal decompression and the use of high doses of antibiotics, fluid, correct acid,